Santa Fe Trail Scenic and Historic Byway - Colorado

Getting to the Byway: ###Denver, CO to Santa Fe Trail Scenic and Historic Byway### * Take I-25 south toward Pueblo. * In Pueblo merge onto US-50 east. * Follow US-50 until La Junta where you will join the byway. Navigating the Byway: * The Colorado section of the Santa Fe Trail starts at the state line of Colorado and Kansas on US 50. * Drive west on US 50 to Gulf Ave in Granada, CO. * Continue west on Gulf Ave to Main St. in Lamar, CO, then continue north to US 50. * Continue west on US 50 to Bent Ave. * Drive south to Ambassador Thompson Blvd, then head west to E. 1st Dr. * Make your way west to Barnes Ave, then south to W. 5th St. * Continue west to Potter Dr. and then southwest to John F. Kennedy Memorial Hwy. * Drive south on John F. Kennedy Memorial Hwy to the state line of Colorado and New Mexico, where the Colorado section ends.