The Ozark Highlands Scenic Byway includes 35 miles of Arkansas
State Scenic Highway 21 from the Ozark National Forest southern
boundary north of Clarksville in Johnson County to the northern
boundary near the Upper Buffalo Wilderness and Buffalo National
River in Newton County. Arkansas State Highway 16 from Fallsville
to Edwards Junction in Newton County joins this route for eight and
one half miles. This is truly a “highlands route,”
traversing ridges between headwaters of the major streams.
It serves as a major travel way for residents, visitors and
commercial vehicles traveling north from Clarksville to
historically major recreation areas and resorts, centers of
commerce and points of local interest. Chief among these are the
Arkansas communities of Harrison, Jasper, Berryville, Eureka
Springs, The Ozark National Forest, The Ozark Highlands Trail,
Buffalo North River and the White River and its tributaries. This
is also a major route of travel from the Interstate highway system
to Missouri and points north.
The outstanding characteristics of this highway are panoramic
views, colorful flora, and rugged terrain. Wildlife is abundant and
it is not uncommon to see white-tail deer, wild turkey, and black
bear, as well as smaller species such as songbirds and squirrels.
Occasionally, bald eagles and golden eagles are also seen. Located
on the byway is Ozone Recreation Area. Significant landmarks
include the escarpment overlook of the Arkansas River Valley, the
settlements of Ozone, Salus, Fallsville, Edward's Junction and
Mossville.